Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) | 2112737-19-4 | > 96% | C38H76N2O16 | 100 MG
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N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting a specific protein. These molecules function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and not sold to patients.
- Peg-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Tos-PEG3-CH2COOtBu | 1530778-24-5 | 418.50 | 5 G
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Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules designed with two different ligands connected by a linker, one for an E3 ubiquitin ligase and another for the target protein, exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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![Medchemexpress LLC Hydroxylamine, o-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 | C8H18N4O4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202345.png-250.jpg)
Medchemexpress LLC Hydroxylamine, o-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 | C8H18N4O4 | 25 MG
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Aminooxy-PEG3-azide is a bifunctional PEG-based linker bearing an aminooxy group and an azide group, suitable for conjugation chemistry. It serves as a non-cleavable three-unit PEG spacer for synthesis of antibody-drug conjugates and PROTACs, and enables click chemistry reactions such as CuAAC and SPAAC.
- Used as a non-cleavable three-unit PEG linker for conjugation chemistry
- Contains aminooxy and azide functional groups for orthogonal conjugation
- Compatible with CuAAC and SPAAC click reactions
- Molecular weight 234.25 and formula C8H18N4O4
- Typical purity 95.0% (NMR)
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Medchemexpress LLC 2,4-D isooctyl ester | 25168-26-7 | 97.2% | 10 MM 1 ML
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2,4-D isooctyl ester is a selective herbicide of the chlorophenoxy compound family, known for its higher boiling point, low volatility, and minimal drift. It is effective in managing broadleaf weeds across various environments, including crops, lawns, and forests.
- Selective herbicide
- Chlorophenoxy compound
- Higher boiling point
- Low volatility
- Minimal drift
- Utilized to manage broadleaf weeds
- Suitable for use in crops, lawns, and forests
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Medchemexpress LLC Tr-PEG3-OH | 133699-09-9 | MFCD22574815 | 99.6% | 392.49 g/mol | C25H28O4 | 1 G
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Tr-PEG3-OH is a non-cleavable three-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) and PROTACs. It acts as a short, hydrophilic spacer to improve payload solubility and control spacing between payload and antibody or ligand, supporting efficient conjugation chemistry.
- Non-cleavable three-unit PEG linker suitable for ADC and PROTAC synthesis.
- Provides a short, hydrophilic spacer to improve solubility and reduce aggregation.
- High purity for consistent conjugation performance.
- Compatible with standard organic synthesis and conjugation workflows.
- Available in small research quantities for laboratory use.
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Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | MFCD29267156 | >98% | C38H77NO17 | 50 MG
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a building block and PEG linker used to synthesize various PEG-based linkers. It can easily react with activated NHS esters or carboxylic acid in the presence of EDC or HATU. The t-butyl group can be deprotected under acidic conditions, and it is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Easily reacts with activated NHS esters or carboxylic acid in the presence of EDC or HATU.
- t-butyl group can be deprotected under acidic conditions.
- Functions as a PEG-based PROTAC linker.
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eMolecules 1204669-57-7 | 3-(4-(2-AMINOETHYLAMINO)-1,2,5-OXADIAZOL-3-YL)-4-(3-BROMO-4-FLUOROPHENYL)-1,2,4-OXADIAZOL-5(4H)-ONE HI | AstaTech | MFCD27996217 | 513.066 | C12H11BrFIN6O3 | 95.000 | I.NCCNc1nonc1-c1noc(=O)n1-c1ccc(F)c(Br)c1 | 1g | 410712794
3-(4-(2-AMINOETHYLAMINO)-1,2,5-OXADIAZOL-3-YL)-4-(3-BROMO-4-FLUOROPHENYL)-1,2,4-OXADIAZOL-5(4H)-ONE HI | AstaTech | 1204669-57-7 | MFCD27996217 | 513.066 | C12H11BrFIN6O3 | 95.000 | I.NCCNc1nonc1-c1noc(=O)n1-c1ccc(F)c(Br)c1 | 1g | 410712794
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Medchemexpress LLC Bis-PEG3-NHS ester | 1314378-16-9 | MFCD20227484 | 97.0% | 444.39 g·mol⁻¹ | C18H24N2O11 | 100 MG
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Bis-PEG3-NHS ester is a noncleavable, three-unit polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester termini for amine coupling. It is intended for antibody-agent conjugation and related bioconjugation chemistries, enabling formation of stable amide bonds to primary amines on proteins or small molecules.
- Noncleavable three-unit PEG spacer suitable for antibody-agent conjugation and bioconjugation.
- Two NHS ester reactive termini for efficient amine coupling to primary amines.
- White to off-white solid, convenient for bench handling.
- High purity (97.0%) with CAS 1314378-16-9 and formula C18H24N2O11.
- Storage: powder at -20°C (stable up to 3 years); in solvent at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Biotin-PEG3-SS-azide | 2866429-93-6 | 99.6% | 692.91 | C27H48N8O7S3 | 10 MG
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Biotin-PEG3-SS-azide is a cleavable three-unit polyethylene glycol linker bearing a biotin group and a terminal azide, designed for conjugation chemistry in research applications. It is suitable for click chemistry reactions and as a cleavable linker in the synthesis of antibody-drug conjugates.
- Cleavable disulfide linker provides intracellular release.
- Azide functionality enables CuAAC and strain-promoted cycloaddition.
- PEG3 spacer increases solubility and reduces steric hindrance.
- High purity supports reliable conjugation results.
- Soluble in DMSO at high concentration for in vitro use.
- Recommended storage at low temperature and protection from light to preserve stability.
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Medchemexpress LLC M-PEG5-acid | 81836-43-3 | MFCD20926398 | 95.0% | 280.31 g/mol | C12H24O7 | 1 G
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m-PEG5-acid is a monomethylated polyethylene glycol (PEG) linker terminated with a carboxylic acid group, used as a short spacer in the synthesis of PROTACs and other bioconjugates. It provides a PEG5 (approximately five ethylene oxide units) spacer with a reactive carboxylic acid for standard coupling chemistries.
- Short monomethylated PEG5 spacer with terminal carboxylic acid.
- Useful as a linker in PROTAC and conjugate synthesis.
- Molecular weight ~280.31 g/mol and formula C12H24O7.
- Typical purity around 95.0%.
- Light yellow to light brown liquid; density ~1.107 g/cm3.
- Store sealed, away from moisture; use cold storage for solutions.
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eMolecules 252881-74-6 | NH2-PEG3-C2-Boc | Ambeed | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 100mg | 506388578
NH2-PEG3-C2-Boc | Ambeed | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 100mg | 506388578
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![Medchemexpress LLC 2-[2-(2-azidoethoxy)ethoxy]ethanol | 86520-52-7 | MFCD09753542 | 98.2% | 175.19 g/mol | C6H13N3O3 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000300804.png-250.jpg)
Medchemexpress LLC 2-[2-(2-azidoethoxy)ethoxy]ethanol | 86520-52-7 | MFCD09753542 | 98.2% | 175.19 g/mol | C6H13N3O3 | 1 G
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Azido-PEG3-alcohol (2-[2-(2-azidoethoxy)ethoxy]ethanol, CAS 86520-52-7) is an azide-terminated PEG3 linker designed for click chemistry conjugations and PROTAC linker assembly. It contains a terminal hydroxyl for further functionalization and an azide group compatible with both copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- Azide functional group enables CuAAC and SPAAC conjugations.
- PEG3 spacer increases aqueous solubility and flexibility.
- Small molecular weight (175.19 g/mol) minimizes steric hindrance.
- High purity suitable for synthetic applications and conjugation reactions.
- Terminal hydroxyl allows additional derivatization or coupling.
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Medchemexpress LLC 1,11-bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 25 MG
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BM-PEG3 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) comprise two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These chimeras leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.
- Functions as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Features two distinct ligands connected by a linker
- Ligands target an E3 ubiquitin ligase and a target protein
- Employs the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
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Medchemexpress LLC Ethanol, 2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]- | 60221-37-6 | 98.7% | 25 G
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THP-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs feature two ligands connected by a linker, one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- High purity of 98.7%
- Molecular weight of 234.29
- Chemical formula is C11H22O5
- Appears as a liquid
- Colorless to light yellow
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 100 G
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Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Peg-based protac linker
- Used in the synthesis of protacs
- Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports
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